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Article

MicroRNA Expression Profile and the Role of miR-204 in Corneal Wound Healing

5 Jun 2015

Abstract excerpt

PURPOSE: MicroRNAs (miRNAs) are endogenous short chain (∼ 22-nucleotide) noncoding RNAs that inhibit protein translation through binding to target mRNAs. Recent studies have implied that miRNAs play a regulatory role in corneal development. Here we profile their involvement in corneal epithelial renewal, develop an miRNA-target network that affects wound healing outcome, and investigate the function of miR-204 in...

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PMID: 26047168
DOI: 10.1167/iovs.15-16467

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