Article
[Impact of cytochrome P450 2C19 polymorphisms on outcome of cardiovascular events in clopidogrel-treated Chinese patients after percutaneous coronary intervention].
Zhonghua xin xue guan bing za zhi - 1 Jul 2011
Tang Xiao-Fang, He Chen, Yuan Jin-Qing, Meng Xian-Min, Yang Yue-Jin, Qin Xue-Wen, Qiao Shu-Bin, Liu Hai-Bo, Wu Yong-Jian, Yao Min, Chen Jue, You Shi-Jie, Wu Yuan, Li Jian-Jun, Dai Jun, Chen Ji-Lin, Gao Run-Lin, Chen Zai-Jia
Abstract excerpt
OBJECTIVE: To investigate the impact of cytochrome P450 (CYP) 2C19 681G > A polymorphism on long-term prognosis of clopidogrel-treated Chinese patients after percutaneous coronary intervention (PCI). METHODS: Between January 1, 2009 and August 31,2009, 267 patients with coronary heart disease who received PCI and treated with clopidogrel for 12 months were enrolled. CYP2C19 * 2 was detected by MALDI-TOF MS and...
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