Article
The case for addressing primary resistance mutations to non-nucleoside reverse transcriptase inhibitors to treat children born from mothers living with HIV in sub-Saharan Africa.
Journal of the International AIDS Society - 1 Jan 2014
Kébé Khady, Bélec Laurent, Diop Ndiaye Halimatou, Bousso Gueye Sokhna, Abdallah Malick Diouara Abou, Ngom Safiétou, Rama Diagne Gueye Ndéye, Mbaye Ngagne, Signaté Sy Haby, Mboup Souleymane, Touré Kane Coumba
Abstract excerpt
The prevalence of human immunodeficiency virus (HIV) drug resistance mutations (DRMs) was estimated in 25 untreated infants who were living with HIV-1, younger than 13 months and living in Senegal. Antiretroviral DRMs were detected in 8 of 25 (32%) children. Non-nucleoside reverse transcriptase inhibitor (NNRTI) DRMs were present in all (100%) children whose viruses harboured DRMs: K103N in 43%; Y181C, K101E and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.