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Article

Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity.

Cancer research - 1 Mar 2014

Gomez German G, Volinia Stefano, Croce Carlo M, Zanca Ciro, Li Ming, Emnett Ryan, Gutmann David H, Brennan Cameron W, Furnari Frank B, Cavenee Webster K

Abstract excerpt

The EGF receptor (EGFR) is amplified and mutated in glioblastoma, in which its common mutation (ΔEGFR, also called EGFRvIII) has a variety of activities that promote growth and inhibit death, thereby conferring a strong tumor-enhancing effect. This range of activities suggested to us that ΔEGFR m...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24436148
DOI: 10.1158/0008-5472.CAN-13-2117
PMCID: PMC3947420

Genes

FOXP1
EGFR
EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24436148-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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Suppression of microRNA-9 by mutant EGFR signaling upregulates FOXP1 to enhance glioblastoma tumorigenicity.PMID 24436148Read ↗

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