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Recombination strategies and evolutionary dynamics of the Human enterovirus A global gene pool

15 Jan 2014

Abstract excerpt

We analysed natural recombination in 79 Human enterovirus A strains representing 13 serotypes by sequencing of VP1, 2C and 3D genome regions. The half-life of a non-recombinant tree node in coxsackieviruses 2, 4 and 10 was only 3.5 years, and never more than 9 years. All coxsackieviruses that differed by more than 7 % of the nucleotide sequence in any genome region were recombinants relative to each other....

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PMID: 24425417
DOI: 10.1099/vir.0.060004-0

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