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RNA Recombination Plays a Major Role in Genomic Change during Circulation of Coxsackie B Viruses

27 Feb 2004

Abstract excerpt

RNA recombination has been shown to occur during circulation of enteroviruses, but most studies have focused on poliovirus. To examine the role of recombination in the evolution of the coxsackie B viruses (CVB), we determined the partial sequences of four genomic intervals for multiple clinical isolates of each of the six CVB serotypes isolated from 1970 to 1996. The regions sequenced were the 5'-nontranslated...

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PMID: 14990713
DOI: 10.1128/jvi.78.6.2948-2955.2004

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