Article
Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma.
British journal of cancer - 18 Feb 2014
Dono M, Angelini G, Cecconi M, Amaro A, Esposito A I, Mirisola V, Maric I, Lanza F, Nasciuti F, Viaggi S, Gualco M, Bandelloni R, Truini M, Coviello D A, Zupo S, Mosci C, Pfeffer U
Abstract excerpt
BACKGROUND: Uveal melanoma is the most frequent primary tumour of the eye. It is molecularly clearly distinct from cutaneous melanoma and shows a different pattern of driver mutations. The influence of sunlight ultraviolet (UV) exposure on the aetiology of uveal melanoma is a matter of debate. Th...
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