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Genetic Aspects of Conjunctival Melanoma: A Review

23 Aug 2023

Abstract excerpt

Conjunctival melanoma (CM) is a rare but aggressive cancer. Over the past decade, molecular studies using rapidly advancing technologies have increasingly improved our understanding of CM genetics. CMs are mainly characterized by dysregulated MAPK and PI3K/AKT/mTOR pathways, driven by commonly mutated (BRAF, NRAS, NF1) or less commonly mutated (KIT, PTEN) genes. Another group of genes frequently mutated in CMs...

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Share to Cutaneous Melanoma Detection and Management
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37761808
DOI: 10.3390/genes14091668

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