Article
HTLV-1 infects human mesenchymal stromal cell in vitro and modifies their phenotypic characteristics.
Virology - 20 Jan 2014
Rodrigues Evandra Strazza, de Macedo Mayra Dorigan, Pinto Mariana Tomazini, Orellana Maristela Delgado, Rocha Junior Maurício Cristiano, de Magalhães Danielle Aparecida Rosa, Tanaka Yuetsu, Takayanagui Osvaldo Massaiti, Covas Dimas Tadeu, Kashima Simone
Abstract excerpt
The typical characteristics of mesenchymal stem cells (MSCs) can be affected by inflammatory microenvironment; however, the exact contribution of HTLV-1 to MSC dysfunction remains to be elucidated. In this study, we demonstrated that MSC cell surface molecules VCAM-1 and ICAM-1 are upregulated by...
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