Article
Mesenchymal stem cells fail to trigger effector functions of cytotoxic T lymphocytes.
Journal of leukocyte biology - 1 Oct 2007
Rasmusson Ida, Uhlin Michael, Le Blanc Katarina, Levitsky Victor
Abstract excerpt
Mesenchymal stem cells (MSCs), isolated from adult human bone marrow, have immunomodulatory properties. The functional outcomes of MSCs-CTL interactions remain poorly characterized. In this study, we demonstrate that MSCs remain resistant to CTL lysis, even after pulsing with the specific synthet...
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