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Article

HIV type 1 alters mesenchymal stem cell differentiation potential and cell phenotype ex vivo.

AIDS research and human retroviruses - 1 Feb 2011

Cotter Eoin J, Chew Nicholas, Powderly William G, Doran Peter P

Abstract excerpt

An increased incidence of bone and lipid toxicities is associated with HIV-1 infection and its treatment. Mesenchymal stem cells (MSCs) are multipotent cells that can differentiate into both osteoblasts (OB) and adipocytes (AC). We hypothesize that the interaction of MSC and HIV-1 underlie these...

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Identifiers

PMID: 20929345
DOI: 10.1089/aid.2010.0114

Genes

LPL
MSC
TAT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20929345-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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