Article
Structural insights into the specific recognition of N-heterocycle biodenitrogenation-derived substrates by microbial amide hydrolases.
Molecular microbiology - 1 Mar 2014
Wu Geng, Chen Duoduo, Tang Hongzhi, Ren Yiling, Chen Qihua, Lv Yang, Zhang Zhenyi, Zhao Yi-Lei, Yao Yuxiang, Xu Ping
Abstract excerpt
N-heterocyclic compounds from industrial wastes, including nicotine, are environmental pollutants or toxicants responsible for a variety of health problems. Microbial biodegradation is an attractive strategy for the removal of N-heterocyclic pollutants, during which carbon-nitrogen bonds in N-heterocycles are converted to amide bonds and subsequently severed by amide hydrolases. Previous studies have failed to...
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