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Article

[Association of the ARMS2 gene with clinical features in polypoidal choroidal vasculopathy].

Nippon Ganka Gakkai zasshi - 1 Nov 2013

Sakurada Yoichi

Abstract excerpt

Polypoidal choroidal vasculopathy (PCV) exhibits subretinal and sub-pigment epithelial lesions, as wells as classic choroidal neovascularization. From a genetic point of view, variants of age-related maculopathy susceptibility 2 (ARMS2) A69S and CFH I62V are reported to be strongly associated with PCV. We investigated whether these two major genetic variants are associated with funduscopic manifestations of PCV....

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PMID: 24397185

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ARMS2
CFH

Variants

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