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Article

Protective effect of the Y220C mutant p53 against steatosis: good news?

Journal of cellular physiology - 1 Sept 2014

Gori Manuele, Barbaro Barbara, Arciello Mario, Maggio Roberta, Viscomi Carmela, Longo Alessia, Balsano Clara

Abstract excerpt

Nonalcoholic fatty liver disease (NAFLD) ranges from simple steatosis to steatohepatitis, which may progress to fibrosis, and cirrhosis, leading eventually to hepatocarcinoma development. Recently, cases of hepatocarcinoma have been diagnosed in steatotic patients without nonalcoholic steatohepatitis (NASH) and cirrhosis. The p53 protein, besides its function as tumor suppressor, is emerging as an important...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24395441
DOI: 10.1002/jcp.24550

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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