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The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virus

7 Jan 2014

Abstract excerpt

Human infection by H7N9 influenza virus was first identified in China in March 2013. As of 12 August 2013, a total of 135 documented cases with 44 fatalities had been reported. Genetic and laboratory analyses of the novel H7N9 viruses isolated from patients indicate that these viruses possess several polymerase gene mutations previously associated with human adaptation and potential pandemic capabilities....

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PMID: 24394699
DOI: 10.1099/vir.0.061721-0

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The PB2 E627K mutation contributes to the high polymerase activity and enhanced replication of H7N9 influenza virusPMID 24394699Read ↗

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