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Article

SNPdryad: predicting deleterious non-synonymous human SNPs using only orthologous protein sequences.

Bioinformatics (Oxford, England) - 15 Apr 2014

Wong Ka-Chun, Zhang Zhaolei

Abstract excerpt

MOTIVATION: The recent advances in genome sequencing have revealed an abundance of non-synonymous polymorphisms among human individuals; subsequently, it is of immense interest and importance to predict whether such substitutions are functional neutral or have deleterious effects. The accuracy of such prediction algorithms depends on the quality of the multiple-sequence alignment, which is used to infer how an...

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PMID: 24389653
DOI: 10.1093/bioinformatics/btt769

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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