Article
Identifying functional modules for coronary artery disease by a prior knowledge-based approach.
Gene - 10 Mar 2014
Li Haoli, Zuo Xiaoyu, Ouyang Ping, Lin Meihua, Zhao Zhong, Liang Yan, Zhong Shouqiang, Rao Shaoqi
Abstract excerpt
Until recently, the underlying genetic mechanisms for coronary artery disease (CAD) have been largely unknown, with just a list of genes identified accounting for very little of the disease in the population. Hence, a systematic dissection of the sophisticated interplays between these individual disease genes and their functional involvements becomes essential. Here, we presented a novel knowledge-based approach...
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