Article
Variants in C-reactive protein and IL-6 genes and susceptibility to obstructive sleep apnea in children: a candidate-gene association study in European American and Southeast European populations.
Sleep medicine - 1 Feb 2014
Kaditis Athanasios G, Gozal David, Khalyfa Abdelnaby, Kheirandish-Gozal Leila, Capdevila Oscar Sans, Gourgoulianis Konstantinos, Alexopoulos Emmanouel I, Chaidas Konstantinos, Bhattacharjee Rakesh, Kim Jinkwan, Rodopoulou Paraskevi, Zintzaras Elias
Abstract excerpt
BACKGROUND: Preliminary evidence indicates that variants of the C-reactive protein (CRP) and IL-6 genes might be associated with the presence of obstructive sleep apnea (OSA) in childhood. Thus a candidate-gene association study was conducted to investigate the association of four variants of the CRP gene (1444C/T, -717T/C, 1861C/T, and 1919A/T) and two variants of the IL-6 gene (-174G/C and 597G/A) with OSA in a...
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