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Article

IpsA, a novel LacI-type regulator, is required for inositol-derived lipid formation in Corynebacteria and Mycobacteria.

BMC biology - 30 Dec 2013

Baumgart Meike, Luder Kerstin, Grover Shipra, Gätgens Cornelia, Besra Gurdyal S, Frunzke Julia

Abstract excerpt

BACKGROUND: The development of new drugs against tuberculosis and diphtheria is focused on disrupting the biogenesis of the cell wall, the unique architecture of which confers resistance against current therapies. The enzymatic pathways involved in the synthesis of the cell wall by these pathogens are well understood, but the underlying regulatory mechanisms are largely unknown. RESULTS: Here, we characterize...

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Share to Cell Wall
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Bacterial

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Share to Lipid Metabolism

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Source

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Identifiers

PMID: 24377418
DOI: 10.1186/1741-7007-11-122
PMCID: PMC3899939

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