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Article

ADHD diagnosis may influence the association between polymorphisms in nicotinic acetylcholine receptor genes and tobacco smoking.

Neuromolecular medicine - 1 Jun 2014

Polina Evelise R, Rovaris Diego L, de Azeredo Lucas A, Mota Nina R, Vitola Eduardo S, Silva Katiane L, Guimarães-da-Silva Paula O, Picon Felipe A, Belmonte-de-Abreu Paulo, Rohde Luis A, Grevet Eugenio H, Bau Claiton H D

Abstract excerpt

Polymorphisms in the CHRNA5-CHRNA3-CHRNB4 gene cluster have been shown to be involved in tobacco smoking susceptibility. Considering that attention deficit/hyperactivity disorder (ADHD) not only increases the risk but may also influence the molecular mechanisms of tobacco smoking, we analyzed the association between polymorphisms in the nicotinic acetylcholine receptor genes and tobacco smoking among individuals...

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Identifiers

PMID: 24375168
DOI: 10.1007/s12017-013-8286-2

Genes

CHRNA3
CHRNA5
CHRNB4

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