Article
The genetics of gene expression in complex mouse crosses as a tool to study the molecular underpinnings of behavior traits.
Mammalian genome : official journal of the International Mammalian Genome Society - 1 Feb 2014
Hitzemann Robert, Bottomly Daniel, Iancu Ovidiu, Buck Kari, Wilmot Beth, Mooney Michael, Searles Robert, Zheng Christina, Belknap John, Crabbe John, McWeeney Shannon
Abstract excerpt
Complex Mus musculus crosses provide increased resolution to examine the relationships between gene expression and behavior. While the advantages are clear, there are numerous analytical and technological concerns that arise from the increased genetic complexity that must be considered. Each of these issues is discussed, providing an initial framework for complex cross study design and planning.
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