Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Oncogenic somatic events in tissue-specific stem cells: a role in cancer recurrence?

Ageing research reviews - 1 Jan 2014

Hartwig F P, Nedel F, Collares T, Tarquinio S B C, Nör J E, Demarco F F

Abstract excerpt

Tissue-specific stem cells (TSSCs) are a very unique cell type, with critical and well-defined roles for the homeostasis of high turnover tissues (such as the blood and the skin). Emerging evidence suggests that TSSCs are implicated in malignancies, with several theories being proposed and tested, including many attempts to identify the cells of origin and studies deigned to understand how TSSCs participate in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Proliferation
Share to Neoplasm Recurrence, Local
Share to Neoplasms

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Neoplastic Stem Cells

Share to Oncogenes

Share to Prognosis

Share to Stem Cell Niche

Share to Tumor Microenvironment

Source

Identifiers

PMID: 24374269
DOI: 10.1016/j.arr.2013.12.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Oncogenic somatic events in tissue-specific stem cells: a role in cancer recurrence?PMID 24374269Read ↗

Somatic stem cells and the origin of cancer.Semantic proximity Read ↗

Initiation of Cancer: The Journey From Mutations in Somatic Cells to Epigenetic Changes in Tissue-resident VSELs.Semantic proximity Read ↗

New cancer diagnostics and therapeutics from a ninth 'hallmark of cancer': symmetric self-renewal by mutated distributed stem cells.Semantic proximity Read ↗

Cancer Stem Cells or Tumor Survival Cells?Semantic proximity Read ↗

Stem cells in cancer initiation and progressionSemantic proximity Read ↗

Cancer stem cell (a)symmetry & plasticity: Tumorigenesis and therapy relevanceSemantic proximity Read ↗

Heterogeneity of Neoplastic Stem Cells: Theoretical, Functional, and Clinical ImplicationsSemantic proximity Read ↗

The development of a malignant tumor is due to a desperate asexual self-cloning process in which cancer stem cells develop the ability to mimic the genetic program of germline cellsSemantic proximity Read ↗

Concise Reviews: Cancer Stem Cells: From Concept to CureSemantic proximity Read ↗

Cancer stem cells modulate patterns and processes of evolution in cancersSemantic proximity Read ↗

Cancer stem cells: targeting tumors at the source.Semantic proximity Read ↗

The Long Evolutionary Journey of Cancer from Ancestor to Modern Humans.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.