Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Airway hyperresponsiveness in FVB/N delta F508 cystic fibrosis transmembrane conductance regulator mice.

Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Jul 2014

Bazett Mark, Haston Christina K

Abstract excerpt

BACKGROUND: Airway hyperresponsiveness is a feature of clinical CF lung disease. In this study, we investigated whether the FVB/N ΔF508 CFTR mouse model has altered airway mechanics. METHODS: Mechanics were measured in 12-14week old FVB/N Cftr(tm1Eur) (ΔF508) mice and wildtype littermates using t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bronchial Hyperreactivity
Share to Bronchoalveolar Lavage Fluid
Share to Cystic Fibrosis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cystic Fibrosis Transmembrane Conductance Regulator

Share to Cytokines

Share to Disease Models, Animal

Share to Immunohistochemistry

Source

Identifiers

PMID: 24373976
DOI: 10.1016/j.jcf.2013.11.010

Genes

CFTR
CXCL1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24373976-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 10 closest

Airway hyperresponsiveness in FVB/N delta F508 cystic fibrosis transmembrane conductance regulator mice.PMID 24373976Read ↗

Airway disease phenotypes in animal models of cystic fibrosis.Semantic proximity Read ↗

Nasal abnormalities in cystic fibrosis mice independent of infection and inflammation.Semantic proximity Read ↗

MOUSE MODELS OF AIRWAY RESPONSIVENESS: Physiological Basis of Observed Outcomes and Analysis of Selected Examples Using These Outcome IndicatorsSemantic proximity Read ↗

The "Goldilocks effect" in cystic fibrosis: identification of a lung phenotype in the cftr knockout and heterozygous mouse.Semantic proximity Read ↗

Macrophages from gut-corrected CF mice express human CFTR and lack a pro-inflammatory phenotype.Semantic proximity Read ↗

Lack of CFTR in skeletal muscle predisposes to muscle wasting and diaphragm muscle pump failure in cystic fibrosis mice.Semantic proximity Read ↗

Measuring lung function in mice: the phenotyping uncertainty principle.Semantic proximity Read ↗

Does lack of Cftr gene lead to developmental abnormalities in the lung?Semantic proximity Read ↗

Efficient killing of inhaled bacteria in DeltaF508 mice: role of airway surface liquid composition.Semantic proximity Read ↗

Phenotypic and physiologic characterization of transgenic mice expressing interleukin 4 in the lung: lymphocytic and eosinophilic inflammation without airway hyperreactivity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.