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Article

Systems biology approach to stage-wise characterization of epigenetic genes in lung adenocarcinoma

1 Dec 2013

Abstract excerpt

BACKGROUND: Epigenetics refers to the reversible functional modifications of the genome that do not correlate to changes in the DNA sequence. The aim of this study is to understand DNA methylation patterns across different stages of lung adenocarcinoma (LUAD). RESULTS: Our study identified 72, 93 and 170 significant DNA methylated genes in Stages I, II and III respectively. A set of common 34 significant DNA...

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PMID: 24369052
DOI: 10.1186/1752-0509-7-141

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