Article
An imbalance between frequency of CD4+CD25+FOXP3+ regulatory T cells and CCR4+ and CCR9+ circulating helper T cells is associated with active perennial allergic conjunctivitis.
Clinical & developmental immunology - 1 Jan 2013
Galicia-Carreón J, Santacruz C, Ayala-Balboa J, Robles-Contreras A, Perez-Tapia S M, Garfias Y, Hong E, Jiménez-Martínez M C
Abstract excerpt
Allergic conjunctivitis (AC) is one of the most common eye disorders in ophthalmology. In mice models, it has been suggested that control of allergic conjunctivitis is a delicate balance between Tregs and inflammatory migrating effector cells. Our aim was to evaluate the frequency of Tregs and the frequency of homing receptors expressing cells in peripheral blood mononuclear cells (PBMC) from patients with...
Topics
- Adolescent
- Antigens, Dermatophagoides
- Child
- Child, Preschool
- Conjunctivitis, Allergic
- Cytokines
- Female
- Forkhead Transcription Factors
- Humans
- Immunophenotyping
- Interleukin-2 Receptor alpha Subunit
- Leukocytes, Mononuclear