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Article

Genome-wide methylation patterns provide insight into differences in breast tumor biology between American women of African and European ancestry.

Oncotarget - 15 Jan 2014

Ambrosone Christine B, Young Allyson C, Sucheston Lara E, Wang Dan, Yan Li, Liu Song, Tang Li, Hu Qiang, Freudenheim Jo L, Shields Peter G, Morrison Carl D, Demissie Kitaw, Higgins Michael J

Abstract excerpt

American women of African ancestry (AA) are more likely than European-Americans (EA) to be diagnosed with aggressive, estrogen receptor (ER) negative breast tumors; mechanisms underlying these disparities are poorly understood. We conducted a genome wide (450K loci) methylation analysis to determine if there were differences in DNA methylation patterns between tumors from AA and EA women and if these differences...

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Identifiers

PMID: 24368439
DOI: 10.18632/oncotarget.1599
PMCID: PMC3960204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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