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Article

Racial Variation in Breast Tumor Promoter Methylation in the Carolina Breast Cancer Study

26 Mar 2015

Abstract excerpt

BACKGROUND: African American (AA) women are diagnosed with more advanced breast cancers and have worse survival than white women, but a comprehensive understanding of the basis for this disparity remains unclear. Analysis of DNA methylation, an epigenetic mechanism that can regulate gene expression, could help to explain racial differences in breast tumor clinical biology and outcomes. METHODS: DNA methylation...

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PMID: 25809865
DOI: 10.1158/1055-9965.epi-14-1228

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