Article
Progressive central puberty in a toddler with partial androgen insensitivity.
The Journal of pediatrics - 1 Mar 2014
Dougan Grace C, Uli Naveen, Shulman Dorothy I
Abstract excerpt
A male infant was diagnosed with partial androgen insensitivity caused by a novel mutation in the androgen receptor. At 3.5 months of age, he received 100 mg of testosterone intramuscularly over the course of 3 months to increase phallic size. He developed pubic hair after 5 months and signs of progressive central precocious puberty when re-examined at 17.5 months, which subsequently was suppressed with depot...
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