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Article

Temsirolimus therapy in a patient with lung adenocarcinoma harboring an FBXW7 mutation.

Lung cancer (Amsterdam, Netherlands) - 1 Feb 2014

Villaruz Liza C, Socinski Mark A

Abstract excerpt

We report the identification of an FBXW7 mutation in a patient with adenocarcinoma of the lung, whose tumor had previously been shown to be EGFR and ALK wild type and who had previously progressed on multiple lines of systemic therapy. She experienced both clinical and radiographic benefit from t...

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Source

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Identifiers

PMID: 24360397
DOI: 10.1016/j.lungcan.2013.11.018
PMCID: PMC4836187

Genes

ALK
EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24360397-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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