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Article

Up-Regulated Expression of miR-23a/b Targeted the Pro-Apoptotic Fas in Radiation-Induced thymic Lymphoma

1 Jan 2013

Abstract excerpt

BACKGROUND: MicroRNAs (miRNAs) are small, single-stranded, noncoding RNAs, which usually bind to the 3'-untranslated region of target mRNAs and are capable of inducing posttranscriptional gene regulation by blocking translation or by degrading the target mRNA. However, the expression level of miR-23 in radiation induced carcinogenesis is largely unknown. METHODS: Radiation induced thymic lymphoma model in BALB/c...

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PMID: 24356489
DOI: 10.1159/000356607

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