Article
Macrovascular involvement in a child with atypical hemolytic uremic syndrome.
Pediatric nephrology (Berlin, Germany) - 1 Jul 2014
Ažukaitis Karolis, Loirat Chantal, Malina Michal, Adomaitienė Irina, Jankauskienė Augustina
Abstract excerpt
BACKGROUND: Atypical hemolytic uremic syndrome (aHUS) is a disorder of the complement system which leads to thrombotic microangiopathy. It is caused by either acquired or hereditary defects in the activation or regulation of the alternative complement pathway and is therefore considered to be a disease of local complement dysregulation in microvasculature with predominantly renal involvement. However, extrarenal...
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