Article
Analysis of mutations in the PIK3CA and FGFR3 genes in verrucous epidermal nevus.
Anais brasileiros de dermatologia - 1 Jan 2000
Miranda Ludmilla Queirós, Fracaroli Tainá Scalfoni, Fonseca João Carlos Macedo, Fontenelle Elisa, Curvo Raphael Pedro Machado, Porto Luís Cristóvão, Souto Roberto
Abstract excerpt
Verrucous epidermal nevi are congenital hamartomas composed of keratinocytes and may occur alone or in association with developmental abnormalities. A close relationship between variations in the PIK3CA and FGFR3 genes and the appearance of nevi has been recently reported. Based on that, we performed molecular assays for the identification of E542K, E545G/K and H1047R mutations in the PIK3CA gene and of the R248C...
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