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Article

microRNA-202 suppresses MYCN expression under the control of E2F1 in the neuroblastoma cell line LAN-5

6 Dec 2013

Abstract excerpt

microRNAs (miRNAs) are small non‑coding RNAs that regulate gene expression by binding to the untranslated regions (UTRs) of target mRNAs. Bioinformatic software predicted that MYCN, a gene overexpressed in aggressive neuroblastoma cells, is a target gene of miRNA‑202 (miR‑202) and that the promoter region of miR‑202 contains binding sites for the transcription factor E2F1. The aims of this study were to explore...

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PMID: 24337320
DOI: 10.3892/mmr.2013.1845

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microRNA-202 suppresses MYCN expression under the control of E2F1 in the neuroblastoma cell line LAN-5PMID 24337320Read ↗

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