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Article

The MicroRNA Landscape of MYCN-Amplified Neuroblastoma

7 May 2021

Abstract excerpt

MYCN gene amplification and upregulated expression are major hallmarks in the progression of high-risk neuroblastoma. MYCN expression and function in modulating gene synthesis in neuroblastoma is controlled at virtually every level, including poorly understood regulation at the post-transcriptional level. MYCN modulates the expression of various microRNAs including the miR-17-92 cluster. MYCN mRNA expression...

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Identifiers

PMID: 34026620
DOI: 10.3389/fonc.2021.647737

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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