Article
PhenoMan: phenotypic data exploration, selection, management and quality control for association studies of rare and common variants.
Bioinformatics (Oxford, England) - 1 Feb 2014
Li Biao, Wang Gao, Leal Suzanne M
Abstract excerpt
MOTIVATION: Next-generation sequencing and other high-throughput technology advances have promoted great interest in detecting associations between complex traits and genetic variants. Phenotype selection, quality control (QC) and control of confounders are crucial and can have a great impact on the ability to detect associations. Although there are programs to perform association analyses, e.g. PLINK and...
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