Article
Association of X-ray repair cross-complementing-6 genotypes with childhood leukemia.
Anticancer research - 1 Dec 2013
Pei Jen-Sheng, Lee Yi-Min, Lo Hsueh-Hsia, Hsu Yuan-Nian, Lin Song-Shei, Bau Da-Tian
Abstract excerpt
BACKGROUND: The Non-homologous end-joining repair gene XRCC6/Ku70 plays an important role in the repair of DNA double-strand breaks (DSBs), and has been found to be involved in the carcinogenesis of many types of cancers including oral, prostate, breast and bladder cancer. However, the contribution of XRCC6 to childhood leukemia has yet to be studied. In the present study, we investigated the association of XRCC6...
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