Article
PRDX1 and PRDX6 are repressed in papillary thyroid carcinomas via BRAF V600E-dependent and -independent mechanisms.
International journal of oncology - 1 Feb 2014
Nicolussi Arianna, D'Inzeo Sonia, Mincione Gabriella, Buffone Amelia, Di Marcantonio Maria Carmela, Cotellese Roberto, Cichella Annadomenica, Capalbo Carlo, Di Gioia Cira, Nardi Francesco, Giannini Giuseppe, Coppa Anna
Abstract excerpt
Many clinical studies highlight the dichotomous role of PRDXs in human cancers, where they can exhibit strong tumor-suppressive or tumor-promoting functions. Recent evidence suggests that lower expression of PRDXs correlates with cancer progression in colorectal cancer (CRC) or in esophageal squa...
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