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Article

Autosomal dominant lateral temporal epilepsy (ADLTE): absence of chromosomal rearrangements in LGI1 gene.

Epilepsy research - 1 Mar 2014

Manna Ida, Mumoli Laura, Labate Angelo, Citrigno Luigi, Ferlazzo Edoardo, Aguglia Umberto, Quattrone Aldo, Gambardella Antonio

Abstract excerpt

Mutations of leucine-rich, glioma inactivated 1 (LGI1) gene are found in about half of the families with autosomal dominant lateral temporal epilepsy (ADLTE). More recently a LGI1 heterozygous microdeletion was found in a single ADLTE family, suggesting that submicroscopic chromosomal abnormalities should be investigated in cases negative for LGI1 mutations. This study examines whether microdeletions and...

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Source

Identifiers

PMID: 24315022
DOI: 10.1016/j.eplepsyres.2013.11.011

Genes

LGI1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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