Article
Low penetrance of autosomal dominant lateral temporal epilepsy in Italian families without LGI1 mutations.
Epilepsia - 1 Jul 2013
Michelucci Roberto, Pasini Elena, Malacrida Sandro, Striano Pasquale, Bonaventura Carlo Di, Pulitano Patrizia, Bisulli Francesca, Egeo Gabriella, Santulli Lia, Sofia Vito, Gambardella Antonio, Elia Maurizio, de Falco Arturo, Neve Angela la, Banfi Paola, Coppola Giangennaro, Avoni Patrizia, Binelli Simona, Boniver Clementina, Pisano Tiziana, Marchini Marco, Dazzo Emanuela, Fanciulli Manuela, Bartolini Yerma, Riguzzi Patrizia, Volpi Lilia, de Falco Fabrizio A, Giallonardo Anna Teresa, Mecarelli Oriano, Striano Salvatore, Tinuper Paolo, Nobile Carlo
Abstract excerpt
PURPOSE: In relatively small series, autosomal dominant lateral temporal epilepsy (ADLTE) has been associated with leucine-rich, glioma-inactivated 1 (LGI1) mutations in about 50% of the families, this genetic heterogeneity being probably caused by differences in the clinical characteristics of the families. In this article we report the overall clinical and genetic spectrum of ADLTE in Italy with the aim to...
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