Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Erythrocyte-derived microvesicles amplify systemic inflammation by thrombin-dependent activation of complement.

Arteriosclerosis, thrombosis, and vascular biology - 1 Feb 2014

Zecher Daniel, Cumpelik Arun, Schifferli Jürg A

Abstract excerpt

OBJECTIVE: Transfusion of aged blood has been associated with increased morbidity and mortality in critically ill patients. During storage, erythrocytes release increasing numbers of microvesicles (red blood cell-derived microvesicles [RBC-MV]). We hypothesized that RBC-MV mediate some of the del...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell-Derived Microparticles
Share to Complement Activation
Share to Complement C3

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Erythrocyte Transfusion

Share to Leukopenia

Share to Mice, 129 Strain

Share to Neutrophil Infiltration

Share to Phosphatidylserines

Source

Identifiers

PMID: 24311376
DOI: 10.1161/ATVBAHA.113.302378

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24311376-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Erythrocyte-derived microvesicles amplify systemic inflammation by thrombin-dependent activation of complement.PMID 24311376Read ↗

[Blood transfusion and inflammation as of yesterday, today and tomorrow].Semantic proximity Read ↗

The role of microvesicles in tissue repairSemantic proximity Read ↗

Erythrocyte-derived extracellular vesicles aggravate inflammation by promoting the proinflammatory macrophage phenotype through TLR4-MyD88-NF-κB-MAPK pathway.Semantic proximity Read ↗

Age- and sex-specific differences in blood-borne microvesicles from apparently healthy humansSemantic proximity Read ↗

Heme triggers TLR4 signaling leading to endothelial cell activation and vaso-occlusion in murine sickle cell disease.Semantic proximity Read ↗

Red blood cell alloimmunization is influenced by recipient inflammatory state at time of transfusion in patients with sickle cell diseaseSemantic proximity Read ↗

How Do Red Blood Cells Die?Semantic proximity Read ↗

Lysis and phenotypic modulation of mesenchymal stromal cells upon blood contact triggers anti-inflammatory skewing of the peripheral innate immune repertoire.Semantic proximity Read ↗

MHC class I-specific antibody binding to nonhematopoietic cells drives complement activation to induce transfusion-related acute lung injury in mice.Semantic proximity Read ↗

Red blood cell-derived microparticles: An overviewSemantic proximity Read ↗

Therapeutic potential of oxygen through M101 transportation in reducing vaso-occlusion and hemolysis in a mouse model of sickle cell diseaseSemantic proximity Read ↗

Complexes between C-Reactive Protein and Very Low Density Lipoprotein Delay Bacterial Clearance in Sepsis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.