Article
Coregulation of host-response genes in integument: switchover of gene expression correlation pattern and impaired immune responses induced by dipteran parasite infection in the silkworm, Bombyx mori.
Journal of applied genetics - 1 May 2014
Jayaram Anitha, Pradeep Appukuttan Nair R, Awasthi Arvind K, Murthy Geetha N, Ponnuvel Kangayam M, Sasibhushan Sirigineedi, Rao Guruprasad C
Abstract excerpt
The activation of host response proteins against parasitic infection is dependent on the coregulation of immune gene expression. The infection of commercially important silkworm Bombyx mori through endoparasite Exorista bombycis enhanced host-response gene expression in integument early in the infection and was lowered asymptotically. Principal component analysis (PCA) showed heterogeneity while explaining ∼80 %...
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