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Article

Mutations and seeding of amylin fibril-like oligomers.

The journal of physical chemistry. B - 19 Dec 2013

Bernhardt Nathan A, Berhanu Workalemahu M, Hansmann Ulrich H E

Abstract excerpt

Seeding a protein solution with preformed fibrils can dramatically enhance the growth rate of amyloids. As the seeds do not need to be of the same protein, seeding may account for the observed correlations between amyloid diseases. In an effort to understand better the molecular mechanisms behind cross seeding we have studied in silico the effect of mutations on the seeding of amylin fibrils. Our investigations...

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Identifiers

PMID: 24294935
DOI: 10.1021/jp409777p
PMCID: PMC3893025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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