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Article

Potential mechanisms of aberrant DNA hypomethylation on the x chromosome in uterine leiomyomas.

The Journal of reproduction and development - 7 Mar 2014

Sato Shun, Maekawa Ryo, Yamagata Yoshiaki, Asada Hiromi, Tamura Isao, Lee Lifa, Okada Maki, Tamura Hiroshi, Sugino Norihiro

Abstract excerpt

We recently found that aberrant DNA hypomethylation is more common on the X chromosome than on other chromosomes in uterine leiomyomas by genome-wide DNA methylation profiling. To investigate the mechanism of aberrant hypomethylation on the X chromosome in uterine leiomyomas, we analyzed methylome and transcriptome data from three cases of leiomyomas and the adjacent myometrium. We found that eleven of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Uterine Myomas and Treatments

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Source

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Identifiers

PMID: 24291816
DOI: 10.1262/jrd.2013-095
PMCID: PMC3963299

Genes

TSPYL2
SATB1
HNRNPU
MED12
SMCHD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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