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Article

Quercetin Induces Mitochondrial Biogenesis through Activation of HO-1 in HepG2 Cells

1 Jan 2013

Abstract excerpt

The regeneration of mitochondria by regulated biogenesis plays an important homeostatic role in cells and tissues and furthermore may provide an adaptive mechanism in certain diseases such as sepsis. The heme oxygenase (HO-1)/carbon monoxide (CO) system is an inducible cytoprotective mechanism in mammalian cells. Natural antioxidants can provide therapeutic benefit, in part, by inducing the HO-1/CO system. This...

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PMID: 24288584
DOI: 10.1155/2013/154279

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