Systemic sclerosis, birth order and parity.

Abstract excerpt

AIM: A recent study identified increasing birth order to be a risk factor for the development of systemic sclerosis (SSc). This finding supports the theory that transplacental microchimerism may be a key pathological event in the initiation of SSc. We investigated the relationship between birth order and parity and the age of onset of SSc in South Australia. METHOD: A retrospective analysis of patient data in the...

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