Article
Association of five genetic variants with chronic obstructive pulmonary disease susceptibility and spirometric phenotypes in a Chinese Han population.
Respirology (Carlton, Vic.) - 1 Feb 2014
Yang Jing, Zhou Haixia, Liang Binmiao, Xiao Jun, Su Zhiguang, Chen Hong, Ma Chunlan, Li Dengxue, Feng Yulin, Ou Xuemei
Abstract excerpt
BACKGROUND AND OBJECTIVE: Recent genome-wide association studies have shown associations between variants at five loci (TNS1, GSTCD, HTR4, AGER and THSD4) and chronic obstructive pulmonary disease (COPD) or lung function. However, their association with COPD has not been proven in Chinese Han population, nor have COPD-related phenotypes been studied. The objective of this study was to look for associations...
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