Article
Robust Estimation of Evolutionary Distances with Information Theory.
Molecular biology and evolution - 1 May 2016
Cao Minh Duc, Allison Lloyd, Dix Trevor I, Bodén Mikael
Abstract excerpt
Methods for measuring genetic distances in phylogenetics are known to be sensitive to the evolutionary model assumed. However, there is a lack of established methodology to accommodate the trade-off between incorporating sufficient biological reality and avoiding model overfitting. In addition, as traditional methods measure distances based on the observed number of substitutions, their tend to underestimate...
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