Article
Cost-effectiveness of using CYP2C19 genotype to guide selection of clopidogrel or ticagrelor in Australia.
Pharmacogenomics - 1 Dec 2013
Sorich Michael J, Horowitz John D, Sorich Wassana, Wiese Michael D, Pekarsky Brita, Karnon Jonathan D
Abstract excerpt
AIMS: This study aims to assess the cost-effectiveness in Australia of screening CYP2C19 loss-of-function (LoF) alleles to guide selection of clopidogrel or ticagrelor for individuals with acute coronary syndrome who are likely to undergo coronary stenting. METHODS: Three treatment strategies were compared: universal clopidogrel therapy, universal ticagrelor therapy and genotyping CYP2C19 with use of ticagrelor...
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