Article
Review of pharmacoeconomic evaluation of genotype-guided antiplatelet therapy.
Expert opinion on pharmacotherapy - 1 Apr 2015
Jiang Minghuan, You Joyce H S
Abstract excerpt
INTRODUCTION: Clopidogrel is an antiplatelet agent widely prescribed for acute coronary syndrome (ACS), and it is activated by the CYP enzyme system to active metabolite. CYP2C19 loss-of-function (LOF) allele(s) affect the responsiveness of clopidogrel, but not the new antiplatelet agents (prasugrel and ticagrelor). We reviewed the pharmacoeconomic studies on genotype-guided use of new antiplatelet agents. AREAS...
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