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Article

Gene expression, single nucleotide variant and fusion transcript discovery in archival material from breast tumors.

PloS one - 1 Jan 2013

Norton Nadine, Sun Zhifu, Asmann Yan W, Serie Daniel J, Necela Brian M, Bhagwate Aditya, Jen Jin, Eckloff Bruce W, Kalari Krishna R, Thompson Kevin J, Carr Jennifer M, Kachergus Jennifer M, Geiger Xochiquetzal J, Perez Edith A, Thompson E Aubrey

Abstract excerpt

Advantages of RNA-Seq over array based platforms are quantitative gene expression and discovery of expressed single nucleotide variants (eSNVs) and fusion transcripts from a single platform, but the sensitivity for each of these characteristics is unknown. We measured gene expression in a set of manually degraded RNAs, nine pairs of matched fresh-frozen, and FFPE RNA isolated from breast tumor with the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24278466
DOI: 10.1371/journal.pone.0081925
PMCID: PMC3838386

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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